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Anyone under opioid medication for a certain period may experience withdrawal symptoms, following a sudden termination of doses. Subutex is a combination formulation of buprenorphine and naloxone that serves a dual purpose of treating opioid use disorder and alleviating chronic pain. It has a higher bioavailability intravenously, but generally available in tablet form. One should start taking Subutex pills only after the symptoms have appeared so that it can precipitate an acute withdrawal. The dose is gradually adjusted based on the level of improvement, and maintenance is carried out through treatment. As a partial agonist, these drugs cannot activate receptors enough to cause euphoria, which makes it difficult to be addictive.
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